Epidermal growth factor: high and low molecular weight forms.

نویسندگان

  • J M Taylor
  • S Cohen
  • W M Mitchell
چکیده

In crude homogenates of the submaxillary gland of the male mouse, epidermal growth factor (EGF) activity was found almost entirely in a high molecular weight complex (about 74,000 daltons). This high molecular weight form may be reversibly dissociated into EGF and an EGF-binding protein. EGF was found to have a molecular weight of approximately 6400. The EGF-binding protein has a molecular weight of 29,000, and shows arginyl-esterase activity.

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عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 67 1  شماره 

صفحات  -

تاریخ انتشار 1970